There are a lot of dialysis patients will ask: why they feel skin itching after dialysis. Onset of pruritus rate was 60% -90%. with dialysis time, the symptoms gradually worsened, so that all patients with anxiety,very painful,seriously affecting the quality of life of the patients.Causing the symptoms of kidney deficiency.Skin itching is the most common symptom for patients with chronic renal failure,due to reduce phosphorus excretion,serum phosphorus level rise repeatedly, blood levels of calcium ion decreased, thereby stimulating parathyroid hormone secretion and lead to secondary hyperparathyroidism. The study shows that the secondary parathyroidism can cause skin itching, which may be caused by increased hypercalcemia, calcification and skin irritation of the skin mast cells to release histamine, which increased parathyroid is considered to be an important cause of the disease.Solution: dietary restriction of phosphorus, phosphorus content of less than 600- 1200mg/d, avoid eating bean and animal offal. Application of active vitamin D. Adjust Calcium dialysate calcium concentration appropriate to prevent hypercalcemia. Change the way to scratch an itchy part. The patient should scratching hand pat, cut nails. Especially helps maintain the integrity of the arteriovenous fistula in the ipsilateral arm of the skin, to avoid fistula infection. If the patient have local infection, when aspiration should be avoided, and prescribed the use of antibiotics baiduobang ointment.